What is Plinest®? DNA-Level Skin Rejuvenation with Polynucleotide (PN)
Plinest® is a cellular skin rejuvenation innovation from Italy utilizing high-purity Polynucleotide (PN) extracted from trout DNA. It works to repair and stimulate new skin cell production from within, enhancing collagen and elastin production. This results in hydrated, elastic, and smoother skin while reducing fine lines and naturally restoring degraded skin to a healthy condition. This treatment is supervised by a licensed medical specialist (Lic. No. 37670) to ensure suitability for each individual.
Key points
- Plinest® utilizes high-purity Polynucleotide (PN) from trout DNA to rejuvenate skin at the cellular level.
- It helps stimulate collagen and elastin production, resulting in hydrated, elastic skin and reduced fine lines.
- It comes in 2 main formulations: Plinest Original for the entire face and Plinest Fast for delicate skin around the eyes.
- It is a skin rejuvenation approach focused on natural results without causing overfilling issues.
- Treatment should be performed continuously according to the physician's advice for clear and long-lasting results.
What is Plinest® Polynucleotide (PN) Skin Rejuvenation Innovation?
Plinest® is a skin rejuvenation product in the Polynucleotide (PN) category, developed and manufactured by Mastelli in Italy. Its highlight is the extraction of DNA from trout (Trout Gonad), purified using HPT (Highly Purified Technology) to obtain highly safe PN suitable for medical skin care applications.
This PN molecule can repair and restore skin cells deep at the DNA level, stimulating natural cell regeneration mechanisms and strengthening the internal skin structure.
Mechanism of Action of Plinest® in Skin Rejuvenation
When injected into the dermis layer, Polynucleotide molecules bind to receptors on fibroblast cells, which are the main cells responsible for producing collagen and elastin. This process signals cells to repair and generate structural skin proteins degraded by age.
The result is an increase in collagen and elastin, improving skin density and elasticity. Additionally, it enhances moisture retention capacity, reduces cellular-level inflammation, and promotes the creation of microcapillaries to better supply nutrients to the skin.
Plinest® Product Range Addressing Different Skin Concerns
Plinest® is designed to address different skin concerns across various areas:
• **Plinest Original**: Suitable for full-face, neck, and hand rejuvenation. It enhances overall hydration, elasticity, and radiance, making the skin appear younger and healthier.
• **Plinest Fast**: Specifically formulated for delicate skin areas such as around the eyes and lips. It helps reduce fine lines and dark under-eye circles, and is also suitable for preparing skin before and after laser procedures or surgery.
Post-Injection Care for Plinest®
To maximize treatment efficiency and reduce the chance of side effects, the following guidelines should be followed:
• Avoid wearing makeup for at least 12 hours.
• Abstain from extreme heat exposure, such as saunas, steam rooms, or direct sunlight, for 3–5 days.
• Avoid strenuous exercise for 24–48 hours.
• Refrain from alcoholic beverages for at least 24 hours.
• Regularly apply moisturizing cream and sunscreen.
• Do not massage, press, or rub the injection area for at least 2 days. Individual results may vary. Please follow the guidance of the attending physician (Lic. No. 37670).
FAQ
Does Plinest® injection hurt?
Slight sensations may occur during treatment, but it is generally considered tolerable. The clinic applies a topical anesthetic prior to the procedure to minimize discomfort. Sensations may vary by individual.
How many sessions of Plinest® are required to see results?
The number of sessions depends on individual skin condition and goals. Generally, physicians may recommend 3–4 consecutive sessions spaced 2–3 weeks apart initially, followed by maintenance sessions at appropriate intervals. Consult a physician (Lic. No. 37670) for a personalized treatment plan. Individual results may vary.
Who is Plinest® suitable for?
It is suitable for individuals seeking to restore skin showing signs of aging, dehydrated skin, fine lines, dark under-eye circles, or those wishing to naturally enhance skin quality to be stronger and healthier.
⚠️ Results vary by individual · general information, not personal medical advice · please consult a doctor before deciding.
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